Digsby  

A multiprotocol IM client that lets you manage all your IM, email, and social network accounts from one easy-to-use application. For IM, it brings all your buddies into one merged contact list with support for AIM, MSN, Facebook Chat, Yahoo, ICQ, GTalk, and Jabber. For email, it offers notifications of new emails with message previews, as well as, the ability to perform actions such as "Mark as Read" and "Delete" right from the notification with support for Gmail, Hotmail, Yahoo Mail, AOL/AIM Mail, POP, and IMAP. For social networks, it provides a newsfeed of events on the network and the ability to set status with support for Facebook, Twitter, and MySpace.
Added on: 20-Nov-2008 | hits: 114
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Feedalizr  

A free desktop application that allows you to view, rate and comment on what your friends are sharing online. Tweet, upload pics to Flickr, keep up to date with your friends’ Google Reader, Digg, Tumblr, YouTube and Last.fm posts on FriendFeed. Use unique filters to reduce the noise. Duplications are filtered out.
Added on: 20-Nov-2008 | hits: 124
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Flotzam 

Using this simple application, you can configure what you want to watch and the speed in which you see it. Want to view what your Twitter friends are doing? Want to see the photos your friends have posted on Facebook? Or maybe their photos on Flickr, too? Download now and have all of your photos, Tweets, Diggs, Facebook invites & pokes and feeds come to you!
Added on: 06-Nov-2008 | hits: 87
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iTweet2  

Built-in auto-refresh, search and hashtags
Full follow, block, notifications features
View user bio, location, URL inline with tweets
Watch conversations with "in reply to" links

Added on: 07-Nov-2008 | hits: 100
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LOK8  

a tiny app that auto-updates your Twitter location when you move from place to place. Written by the founder of PBwiki, David Weekly.
Added on: 20-Nov-2008 | hits: 156
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OutTwit  

OutTwit (Outlook + Twitter = OutTwit) Use Twitter from Outlook.
Added on: 20-Nov-2008 | hits: 126
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Pwytter  

Free open source Twitter client written in Python by PJ Coudert. User Interface in 14 languages.
Added on: 20-Nov-2008 | hits: 174
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QckTwit 

A simple Twitter app you can activate anytime by Shift+Alt+T then pops up presenting a text box to enter your update quickly. As soon as you press Ctrl+Enter, it will send update to Twitter and get out of your way. Separate box for URL. If your message exceeds Twitter's limit it will automatically break it down in multiple twits and color those extra chars differently. Open source, requires .Net 3.5
Added on: 06-Nov-2008 | hits: 92
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Snitter 

Snitter is made on the Adobe AIR platform which is both Mac OSX and Microsoft Windows compatible. There is currently a Linux version of Adobe AIR in alpha testing but some functionality is likely missing.
Added on: 06-Nov-2008 | hits: 69
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SociaGami  

sociagami allows you to manage your multiple social network statuses from one beautiful Windows application. sociagami currently supports Myspace, Facebook, and Twitter status.
Added on: 20-Nov-2008 | hits: 180
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